HYDROBIO INX^© series are gelatin-based hydrogel bioinks that provide all the biological benefits of conventional gelatin-based materials in combination with two-photon polymerization processability. It is based on gelatin type B derived from natural collagen which is modified with photo-crosslinkable functional groups enabling efficient multiphoton processing at 780 nm in the presence of the supplied crosslinker.As a result of high reactivity and fast curing speed, the bioinks can be processed at fast writing speeds resulting in a high cell viability. Thanks to its biodegradability, it allows cells to remodel the environment and substitute it with newly formed extracellular matrix over time.HYDROBIO INX^© X100 is a gelatin-based bioink for two photon polymerization applications. It is suitable for cell seeding after processing.

Taale M. et al., 2023, In Situ Fabrication of Constraints for Multicellular Micro-Spheroids Using Two-Photon Lithography, Advanced Functional Materials